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InSIS Webinar Series-2023 Nano-mechanics of bacterial cell wall damage via high aspect ratio bioinspired nanostructures 

Unified platform for Indian Structural Integrity

Speaker: Prof. Kaushik Chatterjee

Department of Materials Engineering, IISc Bangalore

Date: 16th December 2023 (18:00-19:30 IST)

Venue: Online

Link: https://tinyurl.com/InSIS-Seminar-Oct


Functional surfaces with micro-nanoscale topographies are found on several natural surfaces, such as plant leaves, animal skins, and insect wings. More recently, nanostructured surfaces have emerged as a chemical-free alternative for antibacterial surfaces with potential applications in biomedical and nosocomial settings. Such surfaces kill microbes by penetrating and rupturing their cell wall and, therefore, do not exacerbate the already ballooning risk of antimicrobial resistance (AMR). However, successful translation and widespread adoption of this technology depend on the development of a robust understanding of the bacteria-nanostructure interaction and scalable emulation on desired substrates. Over the past decade, our group has been working towards these goals by generating bioinspired nanostructures on ceramics, metals, and polymers and discovered interesting links between the nanomechanical properties of the nanostructures and their ability to impart damage to bacterial cell wall. We have shown that the bulk mechanical properties, as well as the aspect ratio of the nanostructure, are key factors in determining their deformation behavior as nanostructures and that the difficulties in direct imaging of such systems can be circumvented with the help of mathematical and computational modeling. Nanostructured bactericidal surfaces hold significant promise in tackling AMR, and modeling can play an important role in unraveling their true potential. 

Bio-data of speaker:

Prof. Kaushik Chatterjee received his B.E. in Metallurgy from Bengal Engineering College, M.S. in Materials Science and Engineering from the University of Virginia, and Ph.D. in Bioengineering from the Pennsylvania State University.  He worked as a postdoctoral fellow jointly at the National Institute of Standards and Technology and the National Institutes of Health. He joined the Indian Institute of Science, Bangalore, in 2011, where he is currently a Professor in the Departments of Materials Engineering and Bioengineering and serves as the Chair of the Department of Bioengineering. His research group works on materials for biomedical applications and, in recent years, is particularly focused on the use of 3D printing and additive manufacturing technologies for healthcare. He is currently an Associate Editor for the Journal of Materials Chemistry B and Materials Advances.  

Organized by:

InSIS and Center for Structural Integrity of Safety Critical Systems, IIT Madras